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Year Number of Results
1985 2
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1989 7
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1992 8
1993 5
1994 8
1995 9
1996 7
1997 1
1998 11
1999 6
2000 9
2001 10
2002 8
2003 9
2004 10
2005 13
2006 11
2007 13
2008 8
2009 9
2010 18
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450 results

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Page 1
Spitz melanocytic tumours - a review.
Yeh I, Busam KJ. Yeh I, et al. Histopathology. 2022 Jan;80(1):122-134. doi: 10.1111/his.14583. Histopathology. 2022. PMID: 34958498 Review.
Spitz tumours are notorious for the difficulty of distinguishing benign neoplasms with atypical features from melanomas and the related diagnostic uncertainty. Advances in the knowledge of the molecular pathways and genomic aberrations associated with these neoplasms …
Spitz tumours are notorious for the difficulty of distinguishing benign neoplasms with atypical features from melanomas and the relat …
Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
Ng KW, Boumelha J, Enfield KSS, Almagro J, Cha H, Pich O, Karasaki T, Moore DA, Salgado R, Sivakumar M, Young G, Molina-Arcas M, de Carné Trécesson S, Anastasiou P, Fendler A, Au L, Shepherd STC, Martínez-Ruiz C, Puttick C, Black JRM, Watkins TBK, Kim H, Shim S, Faulkner N, Attig J, Veeriah S, Magno N, Ward S, Frankell AM, Al Bakir M, Lim EL, Hill MS, Wilson GA, Cook DE, Birkbak NJ, Behrens A, Yousaf N, Popat S, Hackshaw A; TRACERx Consortium; CAPTURE Consortium; Hiley CT, Litchfield K, McGranahan N, Jamal-Hanjani M, Larkin J, Lee SH, Turajlic S, Swanton C, Downward J, Kassiotis G. Ng KW, et al. Nature. 2023 Apr;616(7957):563-573. doi: 10.1038/s41586-023-05771-9. Epub 2023 Apr 12. Nature. 2023. PMID: 37046094 Free PMC article.
Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma.
Bonilla X, Parmentier L, King B, Bezrukov F, Kaya G, Zoete V, Seplyarskiy VB, Sharpe HJ, McKee T, Letourneau A, Ribaux PG, Popadin K, Basset-Seguin N, Ben Chaabene R, Santoni FA, Andrianova MA, Guipponi M, Garieri M, Verdan C, Grosdemange K, Sumara O, Eilers M, Aifantis I, Michielin O, de Sauvage FJ, Antonarakis SE, Nikolaev SI. Bonilla X, et al. Nat Genet. 2016 Apr;48(4):398-406. doi: 10.1038/ng.3525. Epub 2016 Mar 7. Nat Genet. 2016. PMID: 26950094
Basal cell carcinoma (BCC) of the skin is the most common malignant neoplasm in humans. BCC is primarily driven by the Sonic Hedgehog (Hh) pathway. ...We observed recurrent mutations in MYCN (30%), PPP6C (15%), STK19 (10%), LATS1 (8%), ERBB2 (4%), PIK3CA (2%), and NRAS, KR …
Basal cell carcinoma (BCC) of the skin is the most common malignant neoplasm in humans. BCC is primarily driven by the Sonic Hedgehog …
Recent Advances on Immunohistochemistry and Molecular Biology for the Diagnosis of Adnexal Sweat Gland Tumors.
Macagno N, Sohier P, Kervarrec T, Pissaloux D, Jullie ML, Cribier B, Battistella M. Macagno N, et al. Cancers (Basel). 2022 Jan 18;14(3):476. doi: 10.3390/cancers14030476. Cancers (Basel). 2022. PMID: 35158743 Free PMC article. Review.
Cutaneous sweat gland tumors are a subset of adnexal neoplasms that derive or differentiate into the sweat apparatus. Their great diversity, rarity, and complex terminology make their pathological diagnosis challenging. ...Most of these molecular alterations are represente …
Cutaneous sweat gland tumors are a subset of adnexal neoplasms that derive or differentiate into the sweat apparatus. Their great div …
Melanocytic Skin Neoplasms: What Lesson From Genomic Aberrations?
Urso C. Urso C. Am J Dermatopathol. 2019 Sep;41(9):623-629. doi: 10.1097/DAD.0000000000001341. Am J Dermatopathol. 2019. PMID: 31433323 Review.
Studies on the genomic aberrations in melanocytic neoplasms have shown a complex genomic landscape. In nevi and melanomas, a MAP-kinase pathway activation was generally found, produced by different chromosomal aberrations, including BRAF, NRAS, HRAS, GNAQ, GNA11, BA …
Studies on the genomic aberrations in melanocytic neoplasms have shown a complex genomic landscape. In nevi and melanomas, a MAP-kina …
Atypical Fibroxanthoma.
López L, Vélez R. López L, et al. Arch Pathol Lab Med. 2016 Apr;140(4):376-9. doi: 10.5858/arpa.2014-0495-RS. Arch Pathol Lab Med. 2016. PMID: 27028396 Free article. Review.
Atypical fibroxanthoma is a malignant skin tumor with histologic features similar to those of undifferentiated pleomorphic sarcoma, but lacking its more aggressive behavior. ...However, the lack of K-ras and H-ras mutations in atypical fibroxanthoma compared with undiffere …
Atypical fibroxanthoma is a malignant skin tumor with histologic features similar to those of undifferentiated pleomorphic sarcoma, b …
Inflammatory linear verrucous epidermal nevus (ILVEN) encompasses a spectrum of inflammatory mosaic disorders.
Atzmony L, Ugwu N, Hamilton C, Paller AS, Zech L, Antaya RJ, Choate KA. Atzmony L, et al. Pediatr Dermatol. 2022 Nov;39(6):903-907. doi: 10.1111/pde.15094. Epub 2022 Jul 19. Pediatr Dermatol. 2022. PMID: 35853659 Free PMC article.
BACKGROUND: Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare skin disease characterized by pruritic erythematous scaly plaques distributed along the lines of Blaschko. ...RESULTS: Five patients were enrolled. All had skin lesions from birth or early c …
BACKGROUND: Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare skin disease characterized by pruritic erythematous scaly …
Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression.
Wong CE, Yu JS, Quigley DA, To MD, Jen KY, Huang PY, Del Rosario R, Balmain A. Wong CE, et al. Genes Dev. 2013 Mar 15;27(6):670-82. doi: 10.1101/gad.210427.112. Genes Dev. 2013. PMID: 23512660 Free PMC article.
Epithelial-mesenchymal transition (EMT) is thought to be an important, possibly essential, component of the process of tumor dissemination and metastasis. About 20%-30% of Hras mutant mouse skin carcinomas induced by chemical initiation/promotion protocols have unde …
Epithelial-mesenchymal transition (EMT) is thought to be an important, possibly essential, component of the process of tumor dissemination a …
Schimmelpenning-Feuerstein-Mims syndrome induced by HRAS Gly12Ser somatic mosaic mutation: Case report and literature review.
Ono H, Yamaguchi R, Arai M, Togi S, Ura H, Niida Y, Shimizu A. Ono H, et al. J Dermatol. 2023 Sep;50(9):1213-1215. doi: 10.1111/1346-8138.16822. Epub 2023 May 12. J Dermatol. 2023. PMID: 37170693 Review.
Accordingly, SFMS was suspected. DNA analysis of nevus sebaceous skin and peripheral blood leukocytes showed a pathogenic HRAS variant NM_005343.4:c.34G > A p.(Gly12Ser) in biopsy specimens from different skin layers but not blood, indicating somatic mosai …
Accordingly, SFMS was suspected. DNA analysis of nevus sebaceous skin and peripheral blood leukocytes showed a pathogenic HRAS …
NRAS mutant melanoma--undrugable?
Posch C, Ortiz-Urda S. Posch C, et al. Oncotarget. 2013 Apr;4(4):494-5. doi: 10.18632/oncotarget.970. Oncotarget. 2013. PMID: 23660168 Free PMC article. Review.
Mutations in the three rat sarcoma (RAS) family members NRAS (neuroblastoma-RAS), HRAS (Harvey-RAS) and KRAS (Kirsten-RAS) are found in one third of human cancers. ...
Mutations in the three rat sarcoma (RAS) family members NRAS (neuroblastoma-RAS), HRAS (Harvey-RAS) and KRAS (Kirsten-RAS) are found …
450 results